Antifungal activity of silver nanoparticles on some of fungi

Nasrollahi, A.; Pourshamsian, Kh.; Mansourkiaee, P.

doi:10.7508/ijnd.2010.03.007

Antifungal activity of silver nanoparticles on some of fungi

Document Type : Reasearch Paper

Authors

¹ Department of biology, Faculty of science, Islamic azad university, Tonekabon branch, Tonekabon, Iran.

² Department of chemistry, Faculty of science, Islamic azad university, Tonekabon branch, Tonekabon, Iran.

³ Basic science student, Member of young researchers club, Islamic azad university of Tonekabon, Iran.

10.7508/ijnd.2010.03.007

Abstract

In this study, we investigated the antifungal effects of silver nanoparticles (Ag-Nps) on Candida albicans (ATCC 5027), Saccharomyces cerevisiae (ATCC 5027). Investigating method by using Minimum Inhibitory Concentration (MIC) technique, some of drugs including Amphotericin B, Fluconazole and synthesized Ag-Nps have been obtained on the fungi and the changes on membrane reactions of yeasts have been elucidated by Scanning Electron Microscopy (SEM). The present study indicates Ag-Nps has considerable antifungal activity comparison with other antifungal drugs, so deserving further investigation for clinical applications.

Keywords